The Bachelor of Science in Nursing is a four-year degree program that provides students the adequate training and knowledge necessary for patient care and health care assessment. This program has a Related Learning Experience (RLE) training which allows the students to be exposed to different health care settings and should demonstrate necessary nursing interventions on a patient assigned to him/her.

A graduate of this program is required to take and pass the Nurses Licensure Examination to be considered a Registered Nurse (RN).

OLFU's College of Nursing was the first BSN program to be accredited Level IV in the National Capital Region by the Philippine Association of Colleges and Universities Commission on Accreditation (PACUCOA).  
 
The College's curriculum integrates the following:

• Review programs for examinations necessary for employment in the US: TOEFL (Test of English as a Foreign Language), CGFNS (Commission on Graduates of Foreign Nursing Schools) and NCLEX (National Council Licensure Examination for Registered Nurses);
• Extensive training in nursing informatics
• Quality research activities exposure to students
• Foreign language training